فاس نيوز ميديا جريدة الكترونية جهوية تعنى بشؤون و أخبار جهة فاس مكناس – متجددة على مدار الساعة
The medical journal “Prescrire” revealed in its annual 2026 report that 108 drugs are considered more dangerous than beneficial, including 89 drugs available in France, according to Le Figaro.
The journal explained that the list includes commonly used medications that can cause disproportionate side effects, sometimes leading to hospitalization or even death. The list is updated annually to add new drugs or remove others based on reassessment of the benefit-risk balance or discontinuation of the drug.
In 2026, four new drugs were added due to weak efficacy or disproportionate side effects:
- Andexanet Alpha
- Chondroitin
- Vesolinantant
- Gevapixant
Key Affected Medical Fields:
- Oncology, hematology, and organ transplantation: Defibrotide, Mifamurtide, Nintedanib, Panobinostat, Roxadustat, Trabectedin, Vandetanib, Fenfluramine.
- Cardiology: Aliskiren, Andexanet Alpha, Bezafibrate, Ciprofibrate, Fenofibrate, Dronedarone, Ivabradine, Nicorandil, Olmesartan, Ranolazine, Trimetazidine, Vernakalant.
- Dermatology & Allergy: Finasteride, Mequitazine, Pimecrolimus, Fluoroglucinol, Topical Tacrolimus, Promethazine (injection).
- Diabetes & Nutrition: Alogliptin, Linagliptin, Saxagliptin, Sitagliptin, Vildagliptin, Pioglitazone, Orlistat, Bupropion with Naltrexone.
- Pain & Rheumatism: Nonsteroidal anti-inflammatory drugs (NSAIDs) such as Aceclofenac and Diclofenac; ibuprofen or naproxen recommended if needed.
- Osteoporosis & Muscle Relaxants: Chondroitin, Diacerein, Glucosamine, Mivacurium, Methocarbamol, Thiocolchicoside, Denosumab, Romosozumab.
- Digestive System: Obeticholic acid, Domperidone, Droperidol, Prucalopride, Opium tincture, Glyceryl trinitrate ointment 0.4%.
- Gynecology & Endocrinology: Tibolone, Vesolinantant.
- Neurology, Alzheimer’s & Multiple Sclerosis: Donepezil, Galantamine, Rivastigmine, Memantine, Alemtuzumab, Natalizumab, Teriflunomide, Fenfluramine, Flunarizine, Oxetorone, Ginkgo Biloba.
- Respiratory & ENT: Ambroxol, Bromhexine, Gevapixant, Oxomemazine, Pentoxyverine, Alpha-amylase, decongestants such as Ephedrine, Naphazoline, Oxymetazoline, Pseudoephedrine, Tuaminoheptane, Phenylephrine, Xylometazoline.
- Psychiatry, Addiction Treatment & Urology: Agomelatine, Citalopram, Escitalopram, Duloxetine, Milnacipran, Reboxetine, Venlafaxine, Esketamine nasal spray, Tianeptine, Dapoxetine, Etifoxine, Bupropion, Beptosane poly-sulfate oral.
The journal emphasized the importance of strictly following medical instructions and consulting a doctor or pharmacist before using any of these medications, particularly for chronic conditions or in patients with other health issues that may increase the risk of complications.
Source: Fes News Media
